Focal articular cartilage injuries in the knee are common and can cause severe morbidity and reduced function.The articular cartilage is avascular and has limited ability to heal, and hence, patients with cartilage injuries have increased risk of progressing Wine Tumbler Friend Card to osteoarthritis.Most of the cartilage injuries are located on th
Brown and beige adipocytes utilize a variety of substrates for cold-induced thermogenesis, contributing to the clearance of metabolites in circulation and, consequently, metabolic health.Food-derived compounds that exhibit agonistic activity at temperature-sensitive transient receptor potential channels may serve as cold mimics to elicit thermogene
Focused ultrasound (FUS) is a rapidly developing stimulus technology with the potential to uncover novel mechanosensory dependent cellular processes.Since it is non-invasive, it holds great promise for future therapeutic applications in ORG CHIA SEEDS patients used either alone or as a complement to boost existing treatments.For example, FUS stimul
Abstract Habitat fragmentation is one of the drivers for amphibian population declines globally.Especially in industrialized countries roads disrupt the seasonal migration of amphibians between hibernation and reproduction sites, often ending in roadkills.Thus, a timely installing of temporary mitigation measures is important for amphibian conserva